网络药理学视角下中药治疗支气管哮喘应用与发展探讨

Discussion on the Application and Development of Traditional Chinese Medicine in the Treatment of Bronchial Asthma from the Perspective of Network Pharmacology

摘要: 支气管哮喘作为全球高发的慢性气道炎症性疾病，其传统西药治疗的长期安全性与耐药性局限日益凸显。中医药凭借多成分、多靶点的整体调节优势，在哮喘控制中展现出独特潜力，而网络药理学为解析其复杂机制提供了关键方法论支撑。网络药理学在分析多成分多靶点药物以揭示中药在分子水平上的潜在治疗机制及效应成分方面显示出独特的效果，为从整体角度理解中医药提供了新的方法论视角。本文综述网络药理学在中医药治疗支气管哮喘中的应用现状与发展趋势，为相关研究的技术创新与临床转化提供理论参考。

Abstract: Bronchial asthma, as a chronic airway inflammatory disease with a high incidence worldwide, the long-term safety and drug resistance limitations of traditional Western medicine treatment have become increasingly prominent. Traditional Chinese medicine, with its comprehensive regulatory advantages of multiple components and multiple targets, has demonstrated unique potential in the control of asthma, and network pharmacology provides key methodological support for understanding its complex mechanisms. Network pharmacology has demonstrated unique effects in analyzing multi-component and multi-target drugs to reveal the potential therapeutic mechanisms and effector components of traditional Chinese medicine at the molecular level, providing a new methodological perspective for understanding traditional Chinese medicine from an overall perspective. This article reviews the current application status and development trend of network pharmacology in the treatment of bronchial asthma with traditional Chinese medicine, providing theoretical references for technological innovation and clinical transformation of related research.