胎儿胆囊内回声改变的超声表现和产后结局
Ultrasonic Manifestations of Echo Changes in the Fetal Gallbladder and Postpartum Outcomes
DOI: 10.12677/acm.2026.161226, PDF,    科研立项经费支持
作者: 夏 琦*:浙江中医药大学研究生院,浙江 杭州;嘉兴市妇幼保健院超声科,浙江 嘉兴;陈轶晖:嘉兴市第二医院重症医学科,浙江 嘉兴;凌 利, 沈晓婷, 杨 静#:嘉兴市妇幼保健院超声科,浙江 嘉兴
关键词: 胎儿胆结石产前超声检查胆囊高回声Fetal Gallstones Prenatal Ultrasound Gallbladder Hyperechoic Mass
摘要: 目的:希望通过对部分病例的随访和记录,了解胎儿胆囊高回声的临床结局。我们希望为产前咨询提供帮助。方法:观察胎儿胆囊产前、产后超声检查结果,并对孕妇实验室检查结果进行分析。结果:胎儿胆囊高回声极有可能出生时自行溶解或在后续随访中消失。我们认为男孩的患病率可能更高,并且与母亲胆汁酸水平升高有关。结论:胆囊高回声多在产后2周内溶解消失,预后良好。这方面我们不需要过多干预,定期随访即可。
Abstract: Objective: We hope that through the follow-up and recording of some cases, we can understand the clinical outcome of hyperechoic masses in the fetal gallbladder. We hope to provide help for prenatal counseling. Methods: We observed the results of prenatal and postpartum ultrasound examination of the gallbladder of the fetus and analyzed the laboratory results of pregnant women. Results: The hyperechoic mass of the fetal gallbladder with gallstones is extremely likely to dissolve spontaneously or disappear on subsequent follow-up. We hypothesize that there may be a higher prevalence among boys and that it is associated with elevated bile acid levels. Conclusion: Gallstones usually dissolve and disappear within 2 weeks after delivery, indicating a good prognosis. We don’t need to intervene too much in this regard, just regular follow-up visits.
文章引用:夏琦, 陈轶晖, 凌利, 沈晓婷, 杨静. 胎儿胆囊内回声改变的超声表现和产后结局[J]. 临床医学进展, 2026, 16(1): 1776-1782. https://doi.org/10.12677/acm.2026.161226

参考文献

[1] Boitor-Borza, D., Rotar, I.C., Staicu, A., Constantin, R. and Muresan, D. (2023) Echogenic Content in the Fetal Gallbladder: Systematic Review of Ultrasound Features and Clinical Outcome. Diagnostics, 13, Article 230. [Google Scholar] [CrossRef] [PubMed]
[2] Boitor Borza, D., Rotar, C.I., Oancea, M. and Muresan, D. (2023) Fetal “Gallstones” Are Still an Unsolved Mystery. Case series. Medical Ultrasonography, 25, Article 403. [Google Scholar] [CrossRef] [PubMed]
[3] Annac, G. and Tekin, A.B. (2022) Echogenicities in the Fetal Gallbladder: Prevalence, Sonographic Findings, and Postnatal Outcomes. Journal of Clinical Ultrasound, 50, 74-79. [Google Scholar] [CrossRef] [PubMed]
[4] Schwab, M.E., Braun, H.J., Feldstein, V.A. and Nijagal, A. (2022) The Natural History of Fetal Gallstones: A Case Series and Updated Literature Review. The Journal of Maternal-Fetal & Neonatal Medicine, 35, 4755-4762. [Google Scholar] [CrossRef] [PubMed]
[5] Sepulveda, W. and Wong, A.E. (2020) Echogenic Material in the Fetal Gallbladder: Prevalence, Sonographic Spectrum, and Perinatal Outcome in an Unselected Third-Trimester Population. The Journal of Maternal-Fetal & Neonatal Medicine, 33, 1162-1170. [Google Scholar] [CrossRef] [PubMed]
[6] Zhang, H., Zhu, X., Kang, J., Sun, Y. and Yang, H. (2022) Pregnancy Outcomes of Non-Visualization of the Fetal Gallbladder from a Chinese Tertiary Single Centre and Literature Review. Children, 9, Article 1288. [Google Scholar] [CrossRef] [PubMed]
[7] Ting, Y., So, P., Cheung, K., Lo, T., Ma, T.W. and Leung, T. (2022) Non-Visualisation of Fetal Gallbladder in a Chinese Cohort. Hong Kong Medical Journal, 28, 116-123. [Google Scholar] [CrossRef] [PubMed]
[8] Kahlon, G.K., Zylak, A., Leblanc, P. and Kondamudi, N. (2021) Fetal Gallstones in a Newborn after Maternal COVID‐19 Infection. Case Reports in Pediatrics, 2021, Article ID: 3688173. [Google Scholar] [CrossRef] [PubMed]
[9] Markova, D., Markova, T., Pandya, P. and David, A.L. (2025) Postnatal Outcome after Ultrasound Findings of an Abnormal Fetal Gallbladder: A Systematic Review and Meta‐Analysis. Prenatal Diagnosis, 45, 185-195. [Google Scholar] [CrossRef] [PubMed]
[10] Gică, N., Radoi, A., Gică, C., Panaitescu, A.M., Peltecu, G. and Huluță, I. (2023) Sonographic Detection of Fetal Cholelithiasis. Diagnostics, 13, Article 2900. [Google Scholar] [CrossRef] [PubMed]
[11] 王雅琴, 曾开会, 杨泽宇, 等. 胎儿胆道系统疾病产前超声诊断研究进展[J]. 中华实用诊断与治疗杂志, 2021, 35(6): 639-641.
[12] Birkness‐Gartman, J.E. and Oshima, K. (2022) Liver Pathology in Pregnancy. Pathology International, 72, 1-13. [Google Scholar] [CrossRef] [PubMed]
[13] Sundaram, K.M., Morgan, M.A., Depetris, J. and Arif-Tiwari, H. (2023) Imaging of Benign Gallbladder and Biliary Pathologies in Pregnancy. Abdominal Radiology, 48, 1921-1932. [Google Scholar] [CrossRef] [PubMed]
[14] Avni, F.E., Garel, C., Naccarella, N. and Franchi-Abella, S. (2023) Anomalies of the Fetal Gallbladder: Pre-and Postnatal Correlations. Pediatric Radiology, 53, 602-609. [Google Scholar] [CrossRef] [PubMed]
[15] Shao, S.J., Grimes, A., Rashad, M., Poder, L., Shum, D. and Sobhani, N.C. (2025) Incidence of New, Nonphysiologic Maternal Findings on Fetal Magnetic Resonance Imaging. American Journal of Perinatology, 42, 1186-1191. [Google Scholar] [CrossRef] [PubMed]