关于乳腺癌卵巢转移的1例报道并文献复习

A Case Report and Literature Review on Ovarian Metastasis of Breast Cancer

摘要: 乳腺癌是女性最常见的癌症之一，发病率呈逐年上升趋势，乳腺癌的主要治疗手段是以手术治疗为主的综合治疗辅以放疗、化疗、内分泌治疗和靶向治疗等。卵巢癌是指发生于卵巢上的癌，其中90%~95%为卵巢原发性的癌，另外5%~10%为其它部位原发的癌转移到卵巢。乳腺癌可先局部扩展，后通过淋巴转移、血行转移至骨、肝、肺等，但卵巢转移极为罕见，且预后较差。有乳腺癌病史的患者发生原发性卵巢癌的可能性较继发性卵巢癌高，约为3~7倍。此篇文章主要对乳腺癌卵巢转移的病例进行讨论及文献复习，并为以后乳腺癌卵巢转移的治疗研究提供参考。

Abstract: Breast cancer is one of the most common malignant tumors in women, with its incidence showing an increasing trend year by year. The main treatment for breast cancer is a comprehensive approach centered on surgical treatment, supplemented by radiotherapy, chemotherapy, endocrine therapy, targeted therapy, and other modalities. Ovarian cancer refers to malignant tumors that arise in the ovaries. Among these, 90% to 95% are primary ovarian cancers, while the remaining 5% to 10% are secondary ovarian cancers, which are metastases from primary cancers originating in other parts of the body. Breast cancer can first spread locally, and then metastasize to the bones, liver, lungs, and other organs through lymphatic or hematogenous routes. However, ovarian metastasis of breast cancer is extremely rare, and the prognosis for patients with this condition is relatively poor. For patients with a history of breast cancer, the likelihood of developing primary ovarian cancer is higher than that of developing secondary ovarian cancer, with the former being approximately 3 to 7 times more common than the latter. This article mainly discusses cases of ovarian metastasis from breast cancer and conducts a literature review, aiming to provide a reference for future research on the treatment of ovarian metastasis from breast cancer.