肝硬化与男性勃起功能障碍相关性的研究进展
Research Progress on the Association between Liver Cirrhosis and Erectile Dysfunction in Males
DOI: 10.12677/acm.2026.161307, PDF,   
作者: 谢昀展：右江民族医学院研究生学院，广西 百色；韦高猛*：右江民族医学院附属医院泌尿外科，广西 百色
关键词: 肝硬化；男性勃起功能障碍；综述文献；Liver Cirrhosis； Erectile Dysfunction in Males； Review Article
摘要: 勃起功能障碍(ED)是男性肝硬化患者中普遍存在但常被漏诊的并发症，严重影响患者生活质量。本综述综合了当前关于肝硬化患者ED的流行病学负担、病理生理机制及循证管理方面的证据。肝硬化中ED的多因素病因涉及激素失衡、血管改变、神经因素、药物副作用以及心理因素。诊断方法应包括经过验证的问卷、激素谱分析及专项评估。治疗策略涵盖磷酸二酯酶-5抑制剂、激素疗法、生活方式调整乃至肝移植。本综述为临床医生处理肝硬化患者ED提供了一个实用框架，并强调整合治疗方法的必要性。
Abstract: Erectile dysfunction (ED) is a prevalent yet frequently underdiagnosed complication in male patients with liver cirrhosis, significantly impairing their quality of life. This review synthesizes current evidence regarding the epidemiological burden, pathophysiological mechanisms, and evidence-based management of ED in cirrhotic patients. The multifactorial etiology of ED in cirrhosis involves hormonal imbalances, vascular alterations, neural factors, medication side effects, and psychological contributors. Diagnostic approaches should incorporate validated questionnaires, hormonal profile analysis, and specialized assessments. Treatment strategies encompass phosphodiesterase-5 inhibitors, hormonal therapy, lifestyle modifications, and even liver transplantation. This review provides clinicians with a practical framework for managing ED in cirrhotic patients and emphasizes the necessity of an integrated treatment approach.
文章引用：谢昀展, 韦高猛. 肝硬化与男性勃起功能障碍相关性的研究进展[J]. 临床医学进展, 2026, 16(1): 2455-2462. https://doi.org/10.12677/acm.2026.161307

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