甲状旁腺癌临床诊断与管理

Clinical Diagnosis and Management of Parathyroid Carcinoma

摘要: 甲状旁腺癌是罕见的恶性肿瘤，它的临床表现是甲状旁腺素升高、高钙血症以及全身各个系统的相关症状，它的罕见性，加上其多样化的临床表现，使其诊断特别具有挑战性。近年来随着医疗水平的不断提高，甲状旁腺癌的发现也相对增多，在临床上诊断甲状旁腺癌时应从临床表现、实验室检查、影像学检查、和病理学检查多个方面考虑，早期诊断、早期治疗可以有效改善患者预后。治疗以外科手术治疗为主，手术的彻底性可以有效降低肿瘤的复发。本文旨在对甲状旁腺癌进行一个综述，提高临床医生对甲状旁腺癌的认识，避免漏诊、误诊带来的不良后果。

Abstract: Parathyroid carcinoma is a rare malignant tumor whose clinical manifestations include elevated parathyroid hormone levels, hypercalcemia, and systemic symptoms affecting various organs. Its rarity, coupled with its diverse clinical presentation, renders diagnosis particularly challenging. In recent years, with continuous advances in medical standards, the detection rate of parathyroid carcinoma has relatively increased. Clinically, diagnosis should consider multiple aspects including clinical presentation, laboratory tests, imaging studies, and pathological examination. Early diagnosis and treatment can significantly improve patient prognosis. Surgical intervention remains the primary treatment modality, with thoroughness of resection effectively reducing tumor recurrence. This article aims to provide a comprehensive review of parathyroid carcinoma, enhancing clinicians’ awareness of this condition and thereby preventing the adverse consequences of misdiagnosis or missed diagnosis.