睾丸精原细胞瘤的诊疗进展
Advances in the Diagnosis and Treatment of Testicular Seminoma
DOI: 10.12677/acm.2026.162396, PDF,   
作者: 钟鹏伟, 廖 扬：吉首大学医学院，湖南 吉首；范诗秋*：吉首大学第一附属医院泌尿外科，湖南 吉首
关键词: 睾丸精原细胞瘤；诊断；治疗；Testicular Seminoma； Diagnosis； Treatment
摘要: 睾丸精原细胞瘤(Testicular Seminoma)是睾丸生殖细胞肿瘤(Testicular Germ Cell Tumor, TGCT)最常见的组织学亚型，约占所有TGCT的55%。该病好发于年轻男性，但得益于其对放疗和化疗的高度敏感性，总体预后极佳。近年来，随着影像诊断技术、分子生物学研究、治疗理念的不断革新以及对患者长期生活质量关注的提升，睾丸精原细胞瘤的诊疗模式正在经历深刻的演变。文章总结了睾丸精原细胞瘤当前在诊断影像学、分子标志物、外科手术、放射治疗、化学治疗、靶向与免疫治疗、生育力保护等方面的最新进展，旨在为临床实践提供理论依据和指导，促进睾丸精原细胞瘤的诊疗水平提升。
Abstract: Testicular Seminoma is the most common histological subtype of Testicular Germ Cell Tumor (TGCT), accounting for approximately 55% of all TGCT cases. The disease predominantly affects young males, and its overall prognosis is excellent due to high sensitivity to radiotherapy and chemotherapy. In recent years, with continuous innovations in imaging diagnostic techniques, molecular biology research, and treatment concepts, as well as increased attention to patients’ long-term quality of life, the diagnosis and treatment model of testicular seminoma has undergone profound evolution. This review summarizes the latest advances in the diagnosis (imaging and molecular markers), surgical treatment, radiotherapy, chemotherapy, targeted therapy, immunotherapy, and fertility preservation for testicular seminoma. It aims to provide a theoretical basis and guidance for clinical practice, and promote the improvement of diagnosis and treatment levels for this disease.
文章引用：钟鹏伟, 廖扬, 范诗秋. 睾丸精原细胞瘤的诊疗进展[J]. 临床医学进展, 2026, 16(2): 322-329. https://doi.org/10.12677/acm.2026.162396

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