从“治疗疾病”到“管理健康”：多囊卵巢综合征全生命周期健康管理模式的构建

From “Disease Treatment” to “Health Management”: Constructing a Lifespan Health Model for PCOS

摘要: 多囊卵巢综合征(PCOS)是育龄期女性高发的慢性内分泌代谢性疾病，发病机制复杂且临床表现异质，不仅严重影响女性生殖健康，还与2型糖尿病、代谢综合征、子宫内膜癌等多种疾病的发生发展密切相关，对患者全生命周期的身心健康与生活质量构成持续性威胁。传统医疗模式多以育龄期女性生育需求为核心，易忽视其他年龄阶段患者的健康管理需求。基于此，本文创新性提出以PCOS患者不同生命阶段为核心的全生命周期健康管理模式，系统阐述育龄期无生育要求、围绝经期及绝经后期PCOS患者面临的核心挑战与健康风险，重点探讨各阶段的个性化管理策略，旨在通过精准化、连续性干预预防远期并发症，提升患者全生命周期生活质量，推动PCOS诊疗从疾病治疗向健康管理的模式转型。

Abstract: Polycystic ovary syndrome (PCOS) is a chronic endocrine and metabolic disorder highly prevalent among women of reproductive age. It is characterized by complex pathogenesis and heterogeneous clinical manifestations, which not only severely impact reproductive health but are also closely associated with the development and progression of various conditions such as type 2 diabetes, metabolic syndrome, and endometrial cancer. These factors pose a persistent threat to the physical and mental well-being and overall quality of life of patients throughout their lifespan. Traditional medical models have predominantly focused on addressing the fertility needs of reproductive-aged women, often overlooking the health management requirements of patients in other age groups. In response, this paper innovatively proposes a life-cycle health management model centered on the distinct stages of PCOS patients’ lives. It systematically elucidates the core challenges and health risks faced by PCOS patients with no immediate fertility demands, as well as those in the perimenopausal and postmenopausal stages. Furthermore, it emphasizes personalized management strategies tailored to each phase, aiming to prevent long-term complications through precise and continuous interventions, enhance the quality of life across patients’ entire lifespan, and facilitate a paradigm shift in PCOS care from disease treatment to holistic health management.