基于伏邪理论与“肠道微生物–免疫轴”探讨儿童过敏性体质
Exploring Pediatric Allergic Constitution Based on the Theory of Latent Pathogens and the “Gut Microbiota - Immune Axis”
DOI: 10.12677/tcm.2026.152081, PDF,   
作者: 张以宁：天津中医药大学第一附属医院儿科，天津；王 林*：国家中医针灸临床医学研究中心，天津
关键词: 儿童过敏体质；伏邪理论；微生物免疫轴；Pediatric Allergic Constitution； Latent Pathogen Theory； Microbiota-Immune Axis
摘要: 儿童过敏性疾病已成为临床中相当常见的疾病之一，其迁延难愈，反复发作的特征经常困扰患儿及其家长，对患儿的学习生活造成了极大影响。本文通过对其发病机制的研究，从中医伏邪理论入手，探讨肠道菌群对儿童过敏体质的影响，系统梳理伏邪理论和肠道微生物–免疫轴与儿童过敏性疾病的关系，为治疗小儿过敏性疾病，改善小儿过敏体质提供理论依据。
Abstract: Pediatric allergic diseases have emerged as a prevalent clinical condition, characterized by persistent and recurrent episodes that significantly disrupt children’s quality of life and academic performance. This study investigates the underlying mechanisms of allergic diseases in children by integrating the Traditional Chinese Medicine (TCM) concept of “latent pathogens” with modern insights into the gut microbiota - immune axis. By systematically analyzing the interplay between latent pathogen theory, gut microbiota dynamics, and immune regulation, this paper elucidates their collective role in shaping pediatric allergic constitution. The findings provide a theoretical foundation for developing targeted interventions to manage allergic diseases and improve allergic predispositions in children.
文章引用：张以宁, 王林. 基于伏邪理论与“肠道微生物–免疫轴”探讨儿童过敏性体质[J]. 中医学, 2026, 15(2): 103-109. https://doi.org/10.12677/tcm.2026.152081

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