输血依赖型非重型再生障碍性贫血的中西医治疗进展

Progress in Chinese and Western Medicine Treatment of Transfusion-Dependent Non-Severe Aplastic Anemia (TD-NSAA)

摘要: 输血依赖型非重型再障(TD-NSAA)不同于预后相对较好的非输血依赖型再障(NTD-NSAA)，往往病情迁延，且有向重型再障(SAA)转化的风险。在TD-NSAA的治疗中，往往采用传统的治疗方案如免疫抑制治疗来试验性治疗，或直接启动SAA的治疗方案。而中医辨治TD-NSAA多采用以补肾生血为治疗核心的NTD-NSAA治则，以肾之阴阳偏盛为辨证要点，没有将因久病和长期外来输血的血瘀兼证作为辨治的重点。本文从TD-NSAA的治疗策略以及中医、西医的治疗方案对TD-NSAA的中西医治疗现状展开研究。

Abstract: Transfusion-dependent non-severe aplastic anemia (TD-NSAA) is different from non-transfusion-dependent non-severe aplastic anemia (NTD-NSAA) with relatively good prognosis. It is often prolonged and has the risk of conversion to severe aplastic anemia (SAA). In the treatment of TD-NSAA, traditional treatment regimens such as immunosuppressive therapy are often used for experimental treatment, or direct initiation of SAA treatment. The traditional Chinese medicine treatment of TD-NSAA mostly adopts the NTD-NSAA treatment principle with tonifying kidney and generating blood as the core of treatment, and takes the yin and yang of the kidney as the key point of syndrome differentiation, while does not take the blood stasis and syndrome of long-term disease and long-term external blood transfusion as the focus of treatment. This paper studies the current situation of Chinese and Western medicine treatment of TD-NSAA from the treatment strategy of TD-NSAA and the treatment plan of traditional Chinese medicine and Western medicine.