益气活血法治疗脑小血管病伴非痴呆血管性认知功能损害患者的临床研究
Clinical Research on Vascular Cognitive Impairment No Dementia Treated by Qi-Supplementing and Blood-Activating Method
DOI: 10.12677/TCM.2018.71010, PDF,    科研立项经费支持
作者: 钟 萍, 李士明, 吴 滢：上海中医药大学附属上海市中西医结合医院神经内科，上海；陈 昕：上海交通大学医学院附属第九人民医院神经内科，上海；吴丹红：上海交通大学医学院附属第九人民医院神经内科，上海；复旦大学附属上海市第五人民医院神经内科，上海
关键词: 脑小血管病；非痴呆血管性认知功能损害；痴呆；补阳还五汤；益气活血法；Cerebral Small Vessel Diseases； Vascular Cognitive Impairment no Dementia； Dementia； Buyang Huanwu Decoction； Qi-Supplementing and Blood-Activating Method
摘要: 目的：观察补阳还五汤治疗脑小血管病(CSVD)非痴呆血管性认知功能损害(VCIND)患者的疗效。方法：采用平行队列研究方法，将60例气虚血瘀证脑小血管病患者分为两组(试验过程中2组各脱落1例)。对照组30例给予西医常规治疗，治疗组在对照组基础上给予中药补阳还五汤加减治疗。治疗3个月后进行MMSE和MoCA评分。结果：治疗3个月后，2组MMSE评分和MoCA评分均明显升高(P < 0.05)，且治疗组MMSE评分和MoCA评分均明显高于对照组(P < 0.05)。结论：补阳还五汤对CSVD伴VCIND患者具有较好的治疗效果。
Abstract: Objective: To observe the clinical therapeutic effects of Qi-supplementing and blood-activating method (益气活血法) on vascular cognitive impairment no dementia(VCIND) patients with cere-bral small vessel diseases(CSVD). Methods: Totally 60 patients who met the diagnostic standard were used parallel cohort divided into the control group and the treatment group with 30 cases in each group (two groups each shedding one case during the experiment). The general therapy was given to the patients in both groups, and Buyang Huanwu decoction was used only in the treatment group for 3 months. The scores of MMSE and MoCA before and after treatment were compared. Results: Scores of MMSE and MoCA increased obviously in both groups (P < 0.05), the improvement of the treatment group was more obvious (P < 0.05). Conclusion: Buyang Huanwu decoction has good therapeutic effects on VCIND patients with CSVD.
文章引用：钟萍, 李士明, 吴滢, 陈昕, 吴丹红. 益气活血法治疗脑小血管病伴非痴呆血管性认知功能损害患者的临床研究[J]. 中医学, 2018, 7(1): 58-62. https://doi.org/10.12677/TCM.2018.71010

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