青梅精对乳腺癌、肝癌细胞增殖抑制率的研究

Research on Inhibition Rate of Plum Essence to the Proliferation of Breast Cancer Cells MCF-7 and Liver Cancer Cells HepG2

摘要: 青梅是重要的山区特色水果，青梅精是一种传统的加工食品，据报道有杀菌、抑制肿瘤等作用。本文研究了青梅精对乳腺癌细胞MCF-7和肝癌细胞HepG2的抑制作用，结果显示：青梅精各剂量组都能不同程度的抑制乳腺癌细胞MCF-7和肝癌HepG2细胞的增殖，且呈现明显剂量–效应关系。青梅精浓度5 mg∙mL⁻¹对乳腺癌MCF-7细胞和肝癌HepG2细胞抑制率分别达82.18%和81.22%。

Abstract: Plum is an important characteristic fruit in mountainous area. Plum essence is a traditional processed food. It has been reported that it can kill bacteria and inhibit tumors. In this paper, the inhibitory effect of plum essence on breast cancer cell MCF-7 and hepatoma cell HepG2 was studied. The results showed that plum essence can inhibit the growth of breast cancer cell line MCF-7 and HepG2. The proliferation of breast cancer cells MCF-7 and HepG2 cells was inhibited to varying degrees in all dosage groups, and the dose-effect relationship was obvious. The inhibitory rates of 5 mg∙mL⁻¹ to breast cancer MCF-7 cells and hepatoma HepG2 cells were 82.18% and 81.22%, respectively.