线型双芳基庚烷类衍生物药理作用研究进展
Advances in Pharmacological Studies of Linear Diarylheptanoids Derivatives
摘要: 双芳基庚烷类化合物以1, 7-二苯基庚烷为骨架，是一类具有显著生物活性的天然产物。自1815年双芳基庚烷类化合物的特征化合物姜黄素被发现以来，目前已确定400多种双芳基庚烷类化合物并且可分为线型或大环类化合物。不断深入的研究发现该类化合物还具有抗肿瘤作用、抗炎作用、抗氧化作用、以及抗菌和抗增殖等活性。目前我们对于该类化合物已经有了较为清晰的认识，本文主要从双芳基庚烷类化合物的药理活性的研究成果展开综述。
Abstract: The diarylheptanoids are based on 1,7-diphenylheptane and are a class of l natural products with significant biological activity. Since the discovery of curcumin, a characteristic compound of the bisaryl heptane compound in 1815, more than 400 diarylheptanoids have been identified and can be classified into linear or macrocyclic compounds. Intensive research has found that these compounds also have anti-tumor, anti-inflammatory, anti-oxidative, antibacterial and an-ti-proliferative activities. At present, we have a clear understanding of this class of compounds. This paper mainly reviews the research results of the pharmacological activities of diarylheptanoids.
文章引用：薛海涛, 杨丽, 艾义, 钟杭. 线型双芳基庚烷类衍生物药理作用研究进展[J]. 药物化学, 2019, 7(2): 13-18. https://doi.org/10.12677/HJMCe.2019.72003

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