经皮神经低频电刺激治疗慢性头痛的随机对照研究

Randomized Controlled Trials on Treatment of Chronic Headache by Low Frequency Transcutaneous Eletrical Nerve Stimulation

摘要: 目的：验证经皮神经低频电刺激仪治疗慢性头痛的有效性与安全性。方法：选取2018年3月至2018年10月诊断患有慢性头痛的120例患者作为研究对象，随机分为试验组和对照组，分别应用两种经皮神经低频电刺激仪进行治疗，每天一次，每次20分钟；治疗时间为一周。结果：试验组和对照组有效率分别为94.74%和92.73%；不良事件发生率分别为18.33%和30.51%。不良事件基本为电刺激引起的短暂轻微不良反应，包括皮肤刺痛、头晕和困倦。严重不良事件发生率均为0.00%。结论：经皮神经低频电刺激仪可以有效地治疗慢性头痛，不良反应轻，安全性好。

Abstract: Objective: To investigate the curative effectiveness and safety of low frequency transcutaneous eletrical nerve stimulation on treatment of chronic headache. Methods: Between March and October 2018, 120 patients with chronic headache were selected. They were randomly divided into experimental group and control group. Two kinds of the low frequency transcutaneous eletrical nerve stimulators were used for treatment, once a day for 20 minutes each time. The duration of treatment is one week. Results: A total of 112 patients were followed up, the dropout rate was 6.67%. The effective rate of the experimental group and control group was 94.74% and 92.73% respectively. The incidence of adverse events was 18.33% and 30.51% respectively. The adverse events were mainly transient mild adverse reactions induced by electrical stimulation including skin tingling, dizziness and drowsiness. The incidence of serve adverse events was 0.00%. There were no significant differences between the two groups (P > 0.05). Conclusions: Low frequency transcutaneous eletrical nerve stimulation can effectively treat chronic headache with mild adverse reactions and good safety.