桑叶多糖的分离纯化及其体外降血糖降血脂活性
Isolation of Mulberry Leaf Polysaccharide and Its Hypoglycemic and Lipid-Lowering Activity
DOI: 10.12677/HJFNS.2020.91007, PDF,  被引量    国家自然科学基金支持
作者: 付式杰, 杨 柳, 李井雷*:合肥工业大学,食品与生物工程学院,安徽 合肥
关键词: 桑叶多糖纯化体外实验降血糖降血脂Mulberry Polysaccharide Purification In Vitro Experiment Hypoglycemic Hypolipidemic
摘要: 桑叶多糖是桑叶中重要的功效成分,本研究采用水提法获得桑叶多糖粗提物,savage法脱蛋白,过氧化氢脱色后,获得桑叶多糖(MLP)。体外实验结果显示MLP可以显著抑制α-葡萄糖苷酶、淀粉酶、脂肪酶活性,并对胆酸盐具有较强的结合能力。研究结果表明,MLP具有较强的降血糖和降血脂活性,有望为相关疾病的预防和治疗提供一定的辅助作用。
Abstract: Mulberry leaf polysaccharide is an important functional component in mulberry leaf. In this study, a crude extract of mulberry leaf polysaccharide was obtained by water extraction, protein was removed by savage method, and mulberry leaf polysaccharide (MLP) was obtained after decolori-zation by hydrogen peroxide treatment. The results of in vitro experiments show that MLP can significantly inhibit α-glucosidase, amylase, and lipase activities, and has strong binding ability to cholate. The research results show that MLP has strong hypoglycemic and lipid-lowering activities, and is expected to provide certain auxiliary effects for the prevention and treatment of related diseases.
文章引用:付式杰, 杨柳, 李井雷. 桑叶多糖的分离纯化及其体外降血糖降血脂活性[J]. 食品与营养科学, 2020, 9(1): 59-66. https://doi.org/10.12677/HJFNS.2020.91007

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