维生素D可能预防流行性感冒的研究进展
Vitamin D for Prevention of Influenza
DOI: 10.12677/HJFNS.2020.92023, PDF,   
作者: 周建烈*:《今日维生素D》,上海 ;张兴权:美国加州大学圣地亚哥医学院传染病系,美国 拉荷亚
关键词: 维生素D流行性感冒病毒Vitamin D Influenza Virus
摘要: 流行性感冒是传染性强、传播速度快的上呼吸道疾病,其并发症病毒性肺炎会严重影响身体健康。维生素D具有骨骼健康效应和非骨骼健康效应,特别具有免疫调节作用和预防病毒感染作用。流行病学研究、荟萃分析和临床研究结果显示:维生素D可能具有预防流行性感冒的健康效应。为了收集维生素D确实能够预防流行性感冒的更多证据,相关的临床医师和营养学家应该进一步做好较大规模的随机双盲、安慰剂对照研究。当然,所有这些都不能代替通常预防流行性感冒的建议。
Abstract: Influenza is a viral upper respiratory disease with strong infectivity and rapid spread. Its complication, viral pneumonia will seriously affect the health of the body. Vitamin D has the effects of bone health and non-bone health, especially immune regulation and prevention of virus infection. The results of epidemiological study, meta-analysis and clinical research show that vitamin D may have the health effect of preventing influenza. In order to determine more evidence that vitamin D can actually prevent influenza, the relevant clinicians and nutritionists should further do a large-scale randomized double-blind, placebo-controlled study. Of course, none of this can replace the usual advice for the prevention of influenza.
文章引用:周建烈, 张兴权. 维生素D可能预防流行性感冒的研究进展[J]. 食品与营养科学, 2020, 9(2): 177-181. https://doi.org/10.12677/HJFNS.2020.92023

参考文献

[1] Ginde, A.A., Mansbach, J.M. and Camargo Jr., C.A. (2009) Association between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey. Archives of Internal Medicine, 169, 384-390. [Google Scholar] [CrossRef] [PubMed]
[2] Berry, D.J., Hesketh, K., Power, C., et al. (2011) Vitamin D Status Has a Linear Association with Seasonal Infections and Lung Function in British Adults. British Journal of Nutrition, 106, 1433-1440. [Google Scholar] [CrossRef
[3] Zhou, Y.F., Luo, B.A. and Qin, L.L. (2019) The Association between Vitamin D Deficiency and Community-Acquired Pneumonia: A Meta-Analysis of Observational Studies. Medicine (Baltimore), 98, e17252. [Google Scholar] [CrossRef
[4] Martineau, A.R., Jolliffe, D.A., Hooper, R.L., et al. (2017) Vitamin D Supplementation to Prevent Acute Respiratory Tract Infections: Systematic Review and Meta-Analysis of Individual Participant Data. BMJ, 356, i6583.
[5] Charan, J., Goyal, J.P., Saxena, D., et al. (2012) Vitamin D for Prevention of Respiratory Tract Infections: A Systematic Review and Meta-Analysis. Journal of Pharmacology & Pharmacotherapeutics, 3, 300-303. [Google Scholar] [CrossRef
[6] Arihiro, S., Nakashima, A., Matsuoka, M., et al. (2019) Randomized Trial of Vitamin D Supplementation to Prevent Seasonal Influenza and Upper Respiratory Infection in Patients with Inflammatory Bowel Disease. Inflammatory Bowel Diseases, 25, 1088-1095. [Google Scholar] [CrossRef] [PubMed]
[7] 李艳红, 张娴, 张俊涛, 等. 昆明市呼吸道感染儿童维生素D营养状况[J]. 昆明医科大学学报, 2018, 39(11): 67-73.
[8] Gruber-Bzura, B.M. (2018) Vitamin D and Influenza-Prevention or Therapy? International Journal of Molecular Sciences, 19, E2419. [Google Scholar] [CrossRef] [PubMed]