人工培养的蝉花子实体对小鼠免疫功能影响的研究

Effects of Artificial Cultured Cicada Flower Fruiting Body on Immune Function in Mice

摘要: 目的：研究人工培养的蝉花子实体对小鼠免疫功能的影响。方法：实验设低、中、高3个剂量组，分别为0.083 g/kg、0.167 g/kg、0.5 g/kg，相当于人体推荐摄入量的5倍、10倍和30倍，取蒸馏水作为阴性对照组，进行碳廓清实验，小鼠腹腔巨噬细胞吞噬鸡红细胞实验以及NK细胞活性鉴定实验。结果：与对照组相比，中、高剂量组均能提高小鼠的吞噬指数(P < 0.05)；蝉花虫草子实体中剂量组和高剂量组NK细胞活性提高，差异均有显著性差异(P < 0.05)。结论：蝉花子实体能增强巨噬细胞的吞噬能力和NK细胞的杀伤活性。

Abstract: Purpose: To study the effect of artificial cultured cicada flower fruiting body on immune function of mice. Methods: Three dose groups were set up, which were 0.083 g/kg, 0.167 g/kg, 0.5 g/kg, equivalent to 5 times, 10 times and 30 times of the recommended intake of human body. Distilled water was used as negative control group for carbon clearance, mouse peritoneal macrophage phagocytosis of chicken red blood cells and NK cell activity identification. Results: Compared with the control group, the middle and high dose groups could increase the phagocytosis index of mice (P < 0.05). The NK cell activity in the dose group was improved, and the difference was significant (P < 0.05). Conclusion: Cicada flower entity could enhance the phagocytosis of macrophages and kill activity of NK cells.