固体培养的蝉花子实体纯粉对小鼠免疫功能影响的评价研究
Study on the Effect of Solid Cultured Pure Powder of Cicada Flower on Immune Function of Mice
DOI: 10.12677/HJFNS.2020.93033, PDF,    国家自然科学基金支持
作者: 朱 戎, 徐 晴, 郑 蓉*:上海中医药大学附属龙华医院,上海;纪 伟:江苏泛亚虫草健康农场有限公司,江苏 淮安
关键词: 蝉花子实体免疫功能Cordyceps cicadae Fruiting Body Immune Function
摘要: 探讨固体培养的蝉花子实体纯粉对小鼠体液免疫功能的影响。将ICR小鼠随机分为高、中、低剂量组及对照组,分别灌胃不同剂量的蝉花子实体纯粉,对照组灌胃同体积的蒸馏水。通过抗体生成细胞检测及血清溶血素实验评估固体培养的蝉花子实体纯粉对小鼠体液免疫的影响。蝉花子实体纯粉对小鼠脏器/体重比值无显著的影响(包括胸腺和脾脏) (P > 0.05),但能以浓度依赖的方式显著提高小鼠的溶血空斑数及抗体积数(P < 0.01),说明人工固体培养的蝉花子实体纯粉具有显著增强体液免疫力的功能。
Abstract: To investigate the effect of solid cultured cicada flower pure powder on humoral immunity in mice, ICR mice were randomly divided into high, middle and low dose groups and control groups. Dose groups were given different doses of cicada flower pure powder; control group was given the same volume of distilled water. The effect of solid cultured pure powder of cicada flower on humoral immunity of mice was evaluated by detection of antibody producing cells and serum hemolysin test. The results showed that the pure powder had no significant effect on the organ/weight ratio of mice (including thymus and spleen) (P > 0.05), but it could significantly increase the number of hemolytic plaque and the number of antibody in mice by concentration-dependent manner (P < 0.01).
文章引用:朱戎, 徐晴, 郑蓉, 纪伟. 固体培养的蝉花子实体纯粉对小鼠免疫功能影响的评价研究[J]. 食品与营养科学, 2020, 9(3): 250-254. https://doi.org/10.12677/HJFNS.2020.93033

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