Caprini静脉血栓风险评估模型在血液肿瘤伴中心静脉血栓患者中的有效性

Effectiveness of Caprini Venous Thrombosis Risk Assessment Model in Patients with Hematologic Malignancies and Central Venous Thrombosis

摘要: 目的：分析Cabrini评估量表在血液病肿瘤患者深静脉血栓(DVT)的预测价值及有效性。方法：采用回顾性研究方法，选取：2014年6月~2019年6月克拉玛依市中心医院收治的血液病肿瘤患者3487例，收集患者一般资料，深静脉事件数，Caprini模型的40个危险因素，并进行Caprini模型评分、血栓发生风险分层，统计分析其相关性。结果：本研究纳入的1656例血液肿瘤患者中，发生下肢深静脉血栓174例(10.51%)；DVT (102例)和非DVT (72例)两组患者一般资料调查结果均无显著差异；DVT患者Caprini评分(12.56 ± 3.721)高于非DVT (6.72 ± 2.89)，差异有统计学意义(P < 0.01)；DVT风险均为高危及以上等级，极高危患者所占比例最高，达到98.04%，与低危组患者相比，极高危组患者DVT风险显著增高，表明Caprini评分与静脉血栓形成具有较好相关性。结论：Caprini静脉血栓风险评估可以较好的预测肿瘤患者下肢深静脉血栓的发生，临床实用性强。

Abstract: Objective: To analyze the predictive value and validity of Caprini assessment scale in deep venous thrombosis (DVT) of hematologic tumor patients. Methods: A retrospective study method was used to select 3487 patients with hematologic diseases and tumor admitted to Karamay Central Hospital from June 2014 to June 2019. The general data of patients, the number of deep venous events, and 40 risk factors of Caprini model were collected. The Caprini model score and the risk stratification of thrombosis were statistically analyzed. Result: In 1656 patients with hematological malignancies, 174 cases (10.51%) had lower extremity deep venous thrombosis; there was no significant difference in general information survey results between DVT (102 cases) and non-DVT (72 cases); Caprini score of DVT patients (12.56 ± 3.721) was higher than that of non-DVT (6.72 ± 2.89), the difference was statistically significant (P < 0.01). Compared with the low-risk group, the risk of DVT in the extremely high-risk group was significantly higher than that in the low-risk group, indicating that there was a good correlation between Caprini score and venous thrombosis. Conclusion: Caprini venous thrombosis risk assessment can better predict the occurrence of lower extremity deep vein thrombosis in tumor patients, and has strong clinical practicability.