联合磺胺类抗生素对蚯蚓的毒性效应
The Effects of Combined Sulfonamides on Earthworms
摘要:
由于磺胺类抗生素的难降解性,有50%~90%运用于畜禽饲料中的磺胺类抗生素无法被降解,会随畜禽的粪便排出,导致土壤环境的污染。因此本实验选用蚯蚓作为指示生物,探究磺胺甲基嘧啶(SM1)、磺胺甲恶唑(SMZ)及磺胺噻唑(ST)在联合作用下对蚯蚓的抗氧化酶系统(超氧化物歧化酶SOD、过氧化物酶POD)的活性的影响。结果表明,不同浓度联合磺胺类抗生素对蚯蚓体内的SOD及POD活性皆有诱导的效果,由此可见,可以用蚯蚓体内的酶活性指标来表征土壤磺胺类抗生素的污染状况。
Abstract:
Due to the difficult degradation of sulfonamides antibiotics, 50%~90% of sulfonamides used in animal feed cannot be degraded, and will be discharged with animal manure. In this study, earth-worm was selected as the indicator organism to explore the effects of sulfadiazine (SMI), sulfamethoxazole (SMZ) and sulfathiazole (ST) on the activities of antioxidant enzyme system (superoxide dismutase SOD and peroxidase POD) of earthworm under the combined modes. The results showed that different concentrations of joint sulfonamide treatments could induce the ac-tivities of SOD and POD in earthworm. In conclusion, both SOD and POD activities could be recog-nized as good biomarkers for evaluating the effects of soil sulfonamide exposure.
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