鲟鳇鱼子提取物对秀丽隐杆线虫寿命的影响
The Effect of Extract of Caviar on the Lifespan of Caenorhabditis elegans
DOI: 10.12677/HJMCe.2022.102020, PDF,    科研立项经费支持
作者: 李玉娟*, 王义国, 张启明#:中国中医科学院医学实验中心,北京;李国志:抚远东龙鲟业有限公司,黑龙江 抚远;柴方营#:黑龙江科技大学,黑龙江 哈尔滨
关键词: 衰老秀丽隐杆线虫寿命鲟鳇鱼子提取物Aging C. elegans Lifespan Extract of Caviar
摘要: 虽然衰老是生物个体正常生理功能不可逆的衰退过程,但采取相应的措施能够对衰老进程起到一定的延缓作用。本文研究了鲟鳇鱼子提取物对秀丽隐杆线虫寿命的影响。结果表明,不同配方的鲟鳇鱼子提取物对线虫平均寿命、最大寿命均具有延长作用。
Abstract: Aging has been regarded as an irreversible process, but the course of aging can be delayed with the help of prevention efforts. The effect of extract of caviar on aging in C. elegans was studied. The re-sults showed that relative to the control, the extract of caviar treatment caused a significant in-crease in mean lifespan, and maximum lifespan.
文章引用:李玉娟, 王义国, 张启明, 李国志, 柴方营. 鲟鳇鱼子提取物对秀丽隐杆线虫寿命的影响[J]. 药物化学, 2022, 10(2): 204-210. https://doi.org/10.12677/HJMCe.2022.102020

参考文献

[1] Zhou, M., Wang, H., Zeng, X., et al. (2019) Mortality, Morbidity, and Risk Factors in China and Its Provinces, 1990-2017: A Systematic Analysis for the Global Burden of Disease Study 2017. Lancet, 394, 1145-1158. [Google Scholar] [CrossRef
[2] 王蕊. 鲟鱼营养保健功能及其深加工产品的开发研究[J]. 食品研究与开发, 2014, 35(22): 135-138.
[3] 王毅虎, 张兵, 王富荣, 等. 胶原蛋白增强免疫力功能研究[J]. 明胶科学与技术, 2015, 35(3): 137-143.
[4] 陈川. 林水淼“还精”学术思想初探[J]. 中医文献杂志, 2012(3): 30-32.
[5] Amrit, F.R.G., Ratnappan, R., Keith, S.A., et al. (2014) The C. elegans Lifespan Assay Toolkit. Methods, 68, 465-475. [Google Scholar] [CrossRef] [PubMed]
[6] 李春生, 侯荣先. 国内应用寿命试验和衰老动物模型研究抗衰老中药的近十年概况[J]. 中医杂志, 1998, 39(11): 690-693.
[7] Jorgensen, E.M. and Mango, S.E. (2002) The Art and Design of Genetic Screens: Ceanorhabditis elegans. Nature Reviews Genetics, 3, 356-369. [Google Scholar] [CrossRef] [PubMed]
[8] Sulston, J.E. and Horvitz, H.R. (1977) Post-Embryonic Cell Lineages of the Nematode Ceanorhabditis elegans. Developmental Biology, 56, 110-156. [Google Scholar] [CrossRef] [PubMed]
[9] Bargmann, C.I. (1998) Neurobiology of the Ceanorhabditis elegans Genome .Science, 282, 2028-2033. [Google Scholar] [CrossRef] [PubMed]
[10] Gershon, H. and Gershon, D. (2002) Ceanorhabditis ele-gans—A Paradigm for Aging Research: Advantage and Limitations. Mechanisms of Ageing and Development, 123, 261-274. [Google Scholar] [CrossRef