基于GRU-Attention多跳特征融合网络的血压预测模型建立
Establishment of Blood Pressure Prediction Model Based on GRU-Attention Multi-Hop Feature Fusion Network
摘要: 针对当今临床医学对高精度连续无创血压监测方法的需求,本文提出一种基于光电容积脉搏波(PPG)信号与心电图(ECG)信号的多传感器信号特征提取及融合的深度神经网络血压预测模型。通过对经过预处理的信号以基于多跳问答推理机制设计的多跳GRU-Attention网络进行特征融合来实现对动脉血压的预测。预测结果的各项评估指标与Bland-Altman一致性分析表明,该模型的预测效果良好,对临床医学上连续无创血压预测技术的发展具有积极意义。
Abstract: In response to the demand for high-precision continuous non-invasive blood pressure monitoring methods in today’s clinical medicine, this paper proposes a deep neural network blood pressure prediction model based on multi-sensor signal feature extraction and fusion of photoplethysmog-raphy (PPG) signals and electrocardiogram (ECG) signals. The prediction of arterial blood pressure is realized by performing feature fusion on the preprocessed signal with a multi-hop GRU- Attention network designed based on a multi-hop question answering reasoning mechanism. The Bland-Altman consistency analysis of the evaluation indicators of the prediction results shows that the prediction effect of the model is good, and it has positive significance for the development of continuous non-invasive blood pressure prediction technology in clinical medicine.
文章引用:潘睿, 何亚军, 张强. 基于GRU-Attention多跳特征融合网络的血压预测模型建立[J]. 建模与仿真, 2023, 12(3): 2586-2596. https://doi.org/10.12677/MOS.2023.123238

参考文献

[1] Junior, A.D., Murali, S., Rincon, F., et al. (2015) Estimation of Blood Pressure and Pulse Transit Time Using Your Smartphone. Euromicro Conference on Digital System Design, Madeira, 26-28 August 2015, 173-180. [Google Scholar] [CrossRef
[2] Fatemeh, H., Malikeh, P., Ebrahim, et al. (2019) A Chest-Based Continuous Cuffless Blood Pressure Method: Estimation and Evaluation Using Multiple Body Sensors. Information Fusion, 54, 119-127. [Google Scholar] [CrossRef
[3] Thomas, S.S., Nathan, V., Zong, C., et al. (2016) BioWatch: A Nonin-vasive Wrist-Based Blood Pressure Monitor That Incorporates Training Techniques for Posture and Subject Variability. IEEE Journal of Biomedical and Health Informatics, 20, 1291-1300. [Google Scholar] [CrossRef
[4] Geddes, L.A., Voelz, M.H., Babbs, C.F., et al. (1981) Pulse Transit Time as an Indicator of Arterial Blood Pressure. Psychophysiology, 18, 71-74. [Google Scholar] [CrossRef] [PubMed]
[5] Shin, H., Sun, S., Lee, J., Kim, H.C., et al. (2021) Complementary Photoplethysmogram Synthesis from Electrocardiogram Using Generative Adversarial Network. IEEE Access, 9, 70639-70649. [Google Scholar] [CrossRef
[6] 甘永进, 陈辉, 赵地, 等. 基于PPG的血管动力学参数检测研究[J]. 航天医学与医学工程, 2019, 32(6): 523-530.
[7] Khalid, S.G., Zhang, J.F., et al. (2018) Blood Pressure Estimation Using Photoplethysmography Only: Comparison between Different Machine Learning Approaches. Journal of Healthcare En-gineering, 2018, Article ID: 1548647. [Google Scholar] [CrossRef] [PubMed]
[8] Fong, M.W.K., Ng, E.Y.K., Jian, K.E.Z, et al. (2019) SVR Ensemble-Based Continuous Blood Pressure Prediction Using Multi-Channel Photoplethysmogram, Computers in Biology and Medicine, 113, 103-115. [Google Scholar] [CrossRef] [PubMed]
[9] Kachuee, M., Kiani, M.M., Mohammadzade, H., et al. (2019) Cuff-Less Blood Pressure Estimation Algorithms for Continuous Health-Care Monitoring. IEEE Transactions on Biomedical Engineering, 64, 859-869. [Google Scholar] [CrossRef
[10] Thambiraj, G., Gandhi, U., Mangalanathan, U., et al. (2020) Investiga-tion on the Effect of Womersley Number, ECG and PPG Features for Cuffless Blood Pressure Estimation Using Machine Learning. Biomedical Signal Processing and Control, 60, Article ID: 101942. [Google Scholar] [CrossRef
[11] 谢寒霜. 基于脉搏波的无创连续血压检测方法的研究[D]: [硕士学位论文]. 北京: 北京交通大学, 2018.
[12] 方启超. 血氧饱和度检测技术研究——无创脉搏血氧饱和度检测仪的设计[D]: [硕士学位论文]. 南京: 南京理工大学, 2013.
[13] 温亮, 李振波, 陈佳品, 等. 基于高斯拟合的神经网络血压测量算法[J]. 传感器与微系统, 2014, 33(4): 132-134, 138.
[14] Baker, S., Xiang, W. and Atkinson, I. (2021) A Hybrid Neural Net-work for Continuous and Non-Invasive Estimation of Blood Pressure from Raw Electrocardiogram and Photoplethysmogram Waveforms. Computer Methods and Programs in Biomedicine, 207, Article ID: 106191. [Google Scholar] [CrossRef] [PubMed]
[15] Rong, M. and Li, K. (2021) A Multi-Type Features Fusion Neural Net-work for Blood Pressure Prediction Based on Photoplethysmography. Biomedical Signal Processing and Control, 68, Article ID: 102772. [Google Scholar] [CrossRef
[16] Vlachopoulos, C., O’Rourke, M. and Nichols, W.W. (2011) McDonald’s Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles.CRC Press, London. [Google Scholar] [CrossRef