一种人体尿液中氟含量快速检测方法研究

Study on a Rapid Detection Method for Fluoride Content in Human Urine

摘要: 地方性氟中毒(又称地氟病)是与地理环境中氟的丰度密切相关的一种世界性地方性氟中毒，基本病征有氟斑牙、氟骨症以及非骨质氟中毒。贵州省特殊的环境特点使得贵州省成为我国受到地方性氟中毒最为严重的省份之一，区域内经济社会发展也因此受到限制。目前为止，对于地氟病并没有确实有效的治疗方案，因此对于地氟病则主要以防控措施为主，而制定针对地氟病的有效防控则需要建立准确的流行病调查结果。本文开发了一种能够现场快速检测受访者尿液中氟元素的显色检测方法，以实现对受访者进行快速筛查，提高患病人群的准确分类。

Abstract: Endemic fluorosis is a worldwide endemic fluoride closely related to the abundance of fluoride in the geographical environment, and the basic symptoms are dental fluorosis, bone fluorosis, and non-bone fluorosis. The special environmental characteristics of Guizhou Province make Guizhou Province one of the provinces most seriously affected by endemic fluorosis in China, and the economic and social development in the region is also restricted. So far, there is no effective treatment plan for endemic fluorosis, so prevention and control measures are mainly used for endemic fluorosis, and the development of effective prevention and control of endemic fluorosis requires the establishment of accurate epidemiological investigations. In this paper, a chromogenic detection method that can rapidly detect fluoride in the urine of respondents in the field was developed to achieve rapid screening of respondents and improve the accurate classification of sick populations.