分散固相萃取–液相色谱串联质谱法检测动物源性食品中地西泮残留量

Determination of Diazepam Residues in An-imal Derived Foods by Liquid Chromatography Tandem Mass Spectrometry

摘要: 为了测定动物源性食品中地西泮残留，采用分散固相萃取前处理方法，采用液相色谱串联质谱法为的方法测定地西泮，测定结果符合国家要求。线性方程为Y = 110356x，r²为0.9993，在0.05~2.00 ug/L范围内线性良好，方法加标回收率为97.0%~97.5%，相对标准偏差为0.33%~1.43%，该方法操作快速、简单、灵敏度高、试剂用量少、对环境友好、回收率达到满意效果。

Abstract: In order to determine the residue of diazepam in animal derived foods, a dispersion solid-phase extraction pretreatment method was used, and the method of liquid chromatography tandem mass spectrometry was used to determine diazepam. The determination results met the national requirements. The linear equation is Y = 110356x, r² is 0.9993, and the linearity is good in the range of 0.05~2.00 ug/L. The recovery rate of the method with added standard is 97.0%~97.5%, and the relative standard deviation is 0.33%~1.43%. This method is fast, simple, sensitive, has low reagent dosage, is environmentally friendly, and achieves satisfactory recovery rate.