新型冠状病毒感染对新生儿出生结局的影响
Effect of COVID-19 Infection on Neonatal Birth Outcomes
DOI: 10.12677/acm.2024.1461915, PDF,   
作者: 易 怡, 姜 泓*：延安大学附属医院新生儿科，陕西 延安
关键词: 新生儿；新型冠状病毒感染；妊娠；出生结局；Neonates； Novel Coronavirus Infection； Pregnancy； Birth Outcomes
摘要: 冠状病毒病2019 (COVID-19)是由严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)引起的，并于2020年3月被宣布为全球大流行，孕妇和婴儿可能特别容易感染COVID-19，因为怀孕期间的生理变化涉及心肺和免疫系统，这可能导致怀孕期间对SARS-CoV-2感染的反应改变在胎儿发育的关键时期，胎儿可能会接触到SARS-CoV-2。COVID-19与妊娠结局之间关联的性质尚不清楚，涉及COVID-19孕妇的荟萃分析也很有限。以前的审查主要集中在病例报告或病例系列的患病率估计上，这些估计难以解释并且可能存在偏见。
Abstract: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and was declared a global pandemic in March 2020. Pregnant people and infants may be particularly susceptible to COVID-19 because the physiologic changes of pregnancy involve cardiorespiratory and immune systems, which may result in an altered response to SARS-CoV-2 infection in pregnancy. Fetuses may be exposed to SARS-CoV-2 during critical periods of fetal development. The nature of the association between COVID-19 and pregnancy outcomes remains unclear, and meta-analyses involving patients with COVID-19 who are pregnant are limited. Previous reviews have focused mostly on prevalence estimates from case reports or case series that are difficult to interpret and potentially biased.
文章引用：易怡, 姜泓. 新型冠状病毒感染对新生儿出生结局的影响[J]. 临床医学进展, 2024, 14(6): 1316-1320. https://doi.org/10.12677/acm.2024.1461915

参考文献

[1] Garg, I., Shekhar, R., Sheikh, A.B. and Pal, S. (2021) COVID-19 Vaccine in Pregnant and Lactating Women: A Review of Existing Evidence and Practice Guidelines. Infectious Disease Reports, 13, 685-699. [Google Scholar] [CrossRef] [PubMed]
[2] Huntley, B.J.F., Huntley, E.S., Di Mascio, D., Chen, T., Berghella, V. and Chauhan, S.P. (2020) Rates of Maternal and Perinatal Mortality and Vertical Transmission in Pregnancies Complicated by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Co-V-2) Infection. Obstetrics & Gynecology, 136, 303-312. [Google Scholar] [CrossRef] [PubMed]
[3] Wang, L., Shi, Y., Xiao, T., Fu, J., Feng, X., Mu, D., et al. (2020) Chinese Expert Consensus on the Perinatal and Neonatal Management for the Prevention and Control of the 2019 Novel Coronavirus Infection (First Edition). Annals of Translational Medicine, 8, 1-8.
https://atm.amegroups.org/article/view/35751
[4] Nie, R., Wang, S.S., Yang, Q., Fan, C.F., Liu, Y.L., He, W.C., et al. (2020) Clinical Features and the Maternal and Neonatal Outcomes of Pregnant Women with Coronavirus Disease 2019. [Google Scholar] [CrossRef] 
[5] Villar, J., Ariff, S., Gunier, R.B., Thiruvengadam, R., Rauch, S., Kholin, A., et al. (2021) Maternal and Neonatal Morbidity and Mortality among Pregnant Women with and without COVID-19 Infection. JAMA Pediatrics, 175, 817-826. [Google Scholar] [CrossRef] [PubMed]
[6] LaCourse, S.M., Kachikis, A., Blain, M., Simmons, L.E., Mays, J.A., Pattison, A.D., et al. (2020) Low Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 among Pregnant and Postpartum Patients with Universal Screening in Seattle, Washington. Clinical Infectious Diseases, 72, 869-872. [Google Scholar] [CrossRef] [PubMed]
[7] Jamieson, D.J. and Rasmussen, S.A. (2022) An Update on COVID-19 and Pregnancy. American Journal of Obstetrics and Gynecology, 226, 177-186. [Google Scholar] [CrossRef] [PubMed]
[8] Diniz, M.S., Hiden, U., Falcão-Pires, I., Oliveira, P.J., Sobrevia, L. and Pereira, S.P. (2023) Fetoplacental Endothelial Dysfunction in Gestational Diabetes Mellitus and Maternal Obesity: A Potential Threat for Programming Cardiovascular Disease. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1869, Article 166834. [Google Scholar] [CrossRef] [PubMed]
[9] Wastnedge, E.A., Reynolds, R.M., Van Boeckel, S.R., Stock, S.J., Denison, F.C., Maybin, J. and Critchley, H.O. (2020) Pregnancy and COVID-19. Physiological Reviews, 101, 303-318. [Google Scholar] [CrossRef] [PubMed]
[10] Piekos, S.N., Roper, R.T., Hwang, Y.M., Sorensen, T., Price, N.D., Hood, L., et al. (2022) The Effect of Maternal SARS-CoV-2 Infection Timing on Birth Outcomes: A Retrospective Multicentre Cohort Study. The Lancet Digital Health, 4, E95-E104. [Google Scholar] [CrossRef] [PubMed]
[11] Medvedev, M.M. (2020) Management of Mother-Newborn Dyads in the COVID-19 Era. The Lancet Child & Adolescent Health, 4, 710-711. [Google Scholar] [CrossRef] [PubMed]
[12] Sharma, K.S., Sharma, R., Nehra, S., Rajpurohit, N.A., Bhakar, K. and Kumar, D. (2022) COVID-19: Consequences on Pregnant Women and Neonates. Health Sciences Review, 4, Article 100044. [Google Scholar] [CrossRef] [PubMed]
[13] Hu, W., Zhu, Y., Wu, Y., Wang, F. and Qu, F. (2022) Impact of COVID-19 Pandemic on the Pregnancy Outcomes of Women Undergoing Assisted Reproductive Techniques (ARTs): A Systematic Review and Meta-Analysis. Journal of Zhejiang University-SCIENCE B, 23, 655-665. [Google Scholar] [CrossRef] [PubMed]
[14] Pineles, B.L., Goodman, K.E., Pineles, L., O’Hara, L.M., Nadimpalli, G., Magder, L.S., et al. (2021) In-Hospital Mortality in a Cohort of Hospitalized Pregnant and Nonpregnant Patients with COVID-19. Annals of Internal Medicine, 174, 1186-1188. [Google Scholar] [CrossRef] [PubMed]
[15] Jering, K.S., Claggett, B.L., Cunningham, J.W., Rosenthal, N., Vardeny, O., Greene, M.F., et al. (2021) Clinical Characteristics and Outcomes of Hospitalized Women Giving Birth with and without COVID-19. JAMA Internal Medicine, 181, 714-717. [Google Scholar] [CrossRef] [PubMed]
[16] DeSisto, C.L., Wallace, B., Simeone, R.M., Polen, K., Ko, J.Y., Meaney-Delman, D., et al. (2021) Risk for Stillbirth among Women with and without COVID-19 at Delivery Hospitalization—United States, March 2020-September 2021. MMWR. Morbidity and Mortality Weekly Report, 70, 1640-1645. [Google Scholar] [CrossRef] [PubMed]
[17] 滕晓慧, 潘石蕾. 孕妇年龄与妊娠高危因素及妊娠结局的关系[J]. 实用妇产科杂志, 2017, 33(9): 692-696.
[18] 冯富丽. 孕妇年龄与妊娠高危因素及妊娠结局的关系[J]. 中国实用医药, 2023, 18(7): 48-51.
[19] Theiler, R.N., Wick, M., Mehta, R., Weaver, A.L., Virk, A. and Swift, M. (2021) Pregnancy and Birth Outcomes after SARS-CoV-2 Vaccination in Pregnancy. American Journal of Obstetrics & Gynecology MFM, 3, Article 100467. [Google Scholar] [CrossRef] [PubMed]
[20] Fell, D.B., Dhinsa, T., Alton, G.D., Török, E., Dimanlig-Cruz, S., Regan, A.K., et al. (2022) Association of COVID-19 Vaccination in Pregnancy with Adverse Peripartum Outcomes. JAMA, 327, 1478-1487. [Google Scholar] [CrossRef] [PubMed]

为你推荐