八段锦运动疗法联合度洛西汀对老年女性抑郁症患者的治疗效果研究
Study on the Therapeutic Effect of Baduanjin Exercise Therapy Combined with Duloxetine on Elderly Female Patients with Depression
DOI: 10.12677/acm.2024.1472123, PDF,   
作者: 胡义蕊*:青岛市精神卫生中心三科,山东 青岛;徐元光:青岛市精神卫生中心特检科,山东 青岛
关键词: 老年女性抑郁症度洛西汀八段锦认知功能睡眠质量Depression in Elderly Women Duloxetine Baduanjin Exercise Therapy Cognitive Function Sleep Quality
摘要: 目的:探讨八段锦运动疗法联合度洛西汀对老年女性抑郁症患者的情绪(抑郁、焦虑)、认知功能(MMSE)、睡眠质量的影响。方法:从青岛市精神卫生中心收治的80名老年女性抑郁症患者中,采用随机数字表法将其分为观察组和对照组,每组40例。对照组应用度洛西汀治疗,观察组在此基础上配合八段锦运动疗法。两组治疗持续时间均为12周。比较观察组和对照组在治疗前和治疗结束后12周内情绪状态、认知功能和睡眠质量的变化。结果:治疗组治疗后HAMD-24评分、HAMA评分、睡眠质量评分均明显低于对照组(P < 0.05),MMSE评分明显高于对照组(P < 0.05)。结论:八段锦运动疗法联合度洛西汀对于老年女性抑郁症患者的情绪、认知和睡眠功能均具有改善作用。
Abstract: Objective: To investigate the effects of Baduanjin exercise therapy combined with duloxetine on mood (depression, anxiety), cognitive function (MMSE) and sleep quality in elderly female patients with depression. Methods: 80 elderly female patients with depression admitted to Qingdao Mental Health Center were selected and divided into observation group and control group according to random number table method, with 40 cases in each group. The control group was treated with duloxetine, and the observation group was treated with Baduanjin exercise therapy. Both groups were treated for 12 weeks. Changes in mood, cognitive function and sleep quality were compared between the two groups before and 12 weeks after treatment. Results: After treatment, HAMD-24 scores, HAMA scores and sleep quality scores in the treatment group were significantly lower than those in the control group (P < 0.05), and MMSE scores were significantly higher than those in the control group (P < 0.05). Conclusion: Baduanjin exercise therapy combined with duloxetine can improve the emotional, cognitive and sleep functions of elderly female patients with depression.
文章引用:胡义蕊, 徐元光. 八段锦运动疗法联合度洛西汀对老年女性抑郁症患者的治疗效果研究[J]. 临床医学进展, 2024, 14(7): 1132-1137. https://doi.org/10.12677/acm.2024.1472123

参考文献

[1] Alexopoulos, G.S. (2005) Depression in the Elderly. The Lancet, 365, 1961-1970. [Google Scholar] [CrossRef] [PubMed]
[2] 王越, 陈晴, 刘鲁蓉. 中国老年人抑郁检出率及影响因素的Meta分析[J]. 中国全科医学, 2023, 26(34): 4329-4335.
[3] 庞羽, 刘爽. 认知行为疗法联合盐酸度洛西汀对抑郁症患者早期起效的影响及疗效观察[J]. 重庆医学, 2020, 49(22): 3720-3723.
[4] 刘璐, 李晓军, 张潇潇, 等. 盐酸度洛西汀联合盐酸曲唑酮治疗缺血性脑卒中后焦虑抑郁共病状态的效果[J]. 临床和实验医学杂志, 2022, 21(20): 2155-2159.
[5] 陈妍, 李朝晖. 草酸艾司西酞普兰和盐酸度洛西汀治疗抑郁症的药学分析[J]. 北方药学, 2023, 20(3): 91-93.
[6] 熊桂芝, 王爱民, 叶洪江. 2型糖尿病肥胖患者八段锦运动处方的制订与应用[J].中华护理教育, 2019, 16(12): 885-888.
[7] 何涛, 袁琼嘉. 运动疗法对抑郁症影响的国内外研究热点与动态分析[J]. 中国康复医学杂志, 2020, 35(2): 200-204.
[8] Wegner, M., Amatriain-Fernández, S., Kaulitzky, A., Murillo-Rodriguez, E., Machado, S. and Budde, H. (2020) Systematic Review of Meta-Analyses: Exercise Effects on Depression in Children and Adolescents. Frontiers in Psychiatry, 11, Article No. 81. [Google Scholar] [CrossRef] [PubMed]
[9] Hetrick, S.E., McKenzie, J.E., Bailey, A.P., Sharma, V., Moller, C.I., Badcock, P.B., et al. (2021) New Generation Antidepressants for Depression in Children and Adolescents: A Network Meta-Analysis. Cochrane Database of Systematic Reviews, 5, CD013674. [Google Scholar] [CrossRef] [PubMed]
[10] Morris, L., Stander, J., Ebrahim, W., Eksteen, S., Meaden, O.A., Ras, A., et al. (2018) Effect of Exercise versus Cognitive Behavioural Therapy or No Intervention on Anxiety, Depression, Fitness and Quality of Life in Adults with Previous Methamphetamine Dependency: A Systematic Review. Addiction Science & Clinical Practice, 13, Article No. 4. [Google Scholar] [CrossRef] [PubMed]
[11] Chen, H., Yeh, M. and Lee, F. (2006) The Effects of Baduanjin Qigong in the Prevention of Bone Loss for Middle-Aged Women. The American Journal of Chinese Medicine, 34, 741-747. [Google Scholar] [CrossRef] [PubMed]
[12] Xiao, C. and Zhuang, Y. (2015) Effect of Health Baduanjin Qigong for Mild to Moderate Parkinson’s Disease. Geriatrics & Gerontology International, 16, 911-919. [Google Scholar] [CrossRef] [PubMed]
[13] Tao, J., Liu, J., Egorova, N., Chen, X., Sun, S., Xue, X., et al. (2016) Increased Hippocampus-Medial Prefrontal Cortex Resting-State Functional Connectivity and Memory Function after Tai Chi Chuan Practice in Elder Adults. Frontiers in Aging Neuroscience, 8, Article No. 25. [Google Scholar] [CrossRef] [PubMed]
[14] (2023) Statement of Retraction: Baduanjin Exercise for Insomnia: A Systematic Review and Meta-Analysis. Behavioral Sleep Medicine, 21, Article No. 352.
[15] Zou, L., Yeung, A., Quan, X., Hui, S.S., Hu, X., Chan, J.S.M., et al. (2018) Mindfulness-Based Baduanjin Exercise for Depression and Anxiety in People with Physical or Mental Illnesses: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health, 15, Article No. 321. [Google Scholar] [CrossRef] [PubMed]