中西医治疗糖尿病肾病的研究进展

Research Progress in the Treatment of Diabetic Nephropathy with Integrated Traditional Chinese and Western Medicine

摘要: 糖尿病肾病是糖尿病发展至后期较为严重的并发症，本病的主要临床表现为蛋白尿、高血压、水肿以及肾衰竭。本病的发病机制较为复杂，紊乱的代谢、血流变学的改变、氧化应激和炎症改变等是其发病的重要机制。糖尿病患者一旦出现肾脏的并发症时，应积极治疗血压、血糖、血脂及尿蛋白。目前，中西医治疗本病均有着各自的优势，但纯西药或者纯中药治疗本病均不能取得较佳的临床效果，中西医的结合用药更能发挥其各自优势。

Abstract: Diabetic nephropathy is a relatively severe complication that develops in the later stages of diabetes. The main clinical manifestations of this disease include proteinuria, hypertension, edema, and renal failure. The pathogenesis of this disease is complex, with disordered metabolism, hemorheological changes, oxidative stress, and inflammatory alterations being significant mechanisms in its development. When diabetic patients experience renal complications, they should actively manage their blood pressure, blood glucose, blood lipids, and urinary protein. Currently, both traditional Chinese medicine and Western medicine possess their respective strengths in treating this condition. However, neither pure Western medicine nor pure traditional Chinese medicine can achieve optimal clinical outcomes. The combination of traditional Chinese and Western medicine can better harness their individual advantages.