耐药肺结核流行现状及相关研究进展

Prevalence of Drug-Resistant Tuberculosis and Related Research Progress

摘要: 耐药肺结核是指结核病患者感染了耐药的结核分枝杆菌，使得结核病的治疗效果降低，病情加重，增加治疗难度，增加治疗费用，导致病情反复发作，尤其是耐多药肺结核的传染周期长，治疗难度大，治疗费用高，治愈率低，死亡率高。分析耐药肺结核的影响因素，对患者实施个体化治疗至关重要。耐药结核病存在多种治疗策略，化学治疗仍然被视为对抗耐药结核病最为关键的方法。本文将概述国内外耐药结核病的流行状况及其治疗方法，旨在为临床优化与提升耐药结核病的治疗效果提供参考依据。

Abstract: Drug-resistant tuberculosis refers to when tuberculosis patients are infected with drug-resistant Mycobacterium tuberculosis, which reduces the treatment effect of tuberculosis, aggravates the condition, increases the difficulty of treatment, increases the cost of treatment, and leads to repeated attacks of the disease, especially multidrug-resistant tuberculosis, which has a long infection cycle, difficult treatment, high treatment cost, low cure rate and high mortality. It is important to analyze the influencing factors of drug-resistant tuberculosis to implement individualized treatment for patients. There are multiple treatment strategies for drug-resistant TB, and chemotherapy is still considered the most critical approach in the fight against drug-resistant TB. This article will summarize the prevalence and treatment methods of drug-resistant tuberculosis at home and abroad, aiming to provide reference for clinical optimization and improvement of the therapeutic effect of drug-resistant tuberculosis.