基于SiO2@BiOI/PANI的光电化学传感器超灵敏检测葡萄糖
Ultra-Sensitive Detection of Glucose of the Photoelectrochemical Sensor Based on SiO2@BiOI/PANI
摘要: 目的：本研究通过水热法合成碘氧化铋(BiOI)，采用一步混合溶剂热法制备SiO2@BiOI，将其修饰在聚苯胺(PANI)上，制备SiO2@BiOI/PANI复合材料，从而对葡萄糖进行特异性光电化学检测。在可见光照射下，具有高比表面积且表面带有微小的空隙结构的SiO2微球可以有效地吸收光能并产生激发态，逐层堆叠的BiOI纳米花材料能够将光能产生光生电子–空穴对，两者进行复合有助于将产生的电子–空穴对有效分离和传输，提高光电流响应。PANI具有优异的导电性能，能够促进电子转移，有效抑制电子–空穴对的复合，从而实现对葡萄糖的超灵敏检测。该光电传感器检测葡萄糖时的浓度范围为5~200 μmol/L，检出限为1.67 μmol/L，表明SiO2@BiOI/PANI对葡萄糖具有较好的检测效果。该SiO2@BiOI/PANI光电化学传感器具有选择性良好、响应时间快、灵敏度高等优点，对葡萄糖的检测具有重要意义，期待其成为葡萄糖检测领域中一种具有潜力的新型传感器技术。
Abstract: Purpose: In this study, bismuth iodide (BiOI) was synthesised by a hydrothermal method, and SiO2@BiOI was prepared by a one-step hybrid solvothermal method, and then modified on polyaniline (PANI) to prepare SiO2@BiOI/PANI composites for the specific photoelectrochemical detection of glucose. Under visible light irradiation, SiO2 microspheres with high specific surface area and tiny void structure on the surface can effectively absorb light energy and generate excited states, and the layer-by-layer stacking of BiOI nanoflowers can generate photogenerated electron-hole pairs from light energy, and the composite of the two can help to efficiently separate and transport the generated electron-hole pairs to improve the response to photocurrent. PANI has excellent electrical conductivity, which can promote electron transfer and effectively inhibit the complexation of electron-hole pairs, thus achieving ultra-sensitive detection of glucose. The photoelectric sensor detected glucose in the concentration range of 5~200 μmol/L with a detection limit of 1.67 μmol/L, indicating that SiO2@BiOI/PANI has a good detection effect on glucose. The SiO2@BiOI/PANI photoelectrochemical sensor has the advantages of good selectivity, fast response time, high sensitivity, etc., which is of great significance for the detection of glucose, and is expected to become a new sensor technology with potential in the field of glucose detection.
文章引用：周棋香, 黎园, 向永杰, 戴艺文, 陈婷婷. 基于SiO2@BiOI/PANI的光电化学传感器超灵敏检测葡萄糖[J]. 分析化学进展, 2024, 14(3): 200-210. https://doi.org/10.12677/aac.2024.143024

参考文献

[1] Jiang, S., Zhang, Y., Yang, Y., Huang, Y., Ma, G., Luo, Y., et al. (2019) Glucose Oxidase-Instructed Fluorescence Amplification Strategy for Intracellular Glucose Detection. ACS Applied Materials & Interfaces, 11, 10554-10558. [Google Scholar] [CrossRef] [PubMed]
[2] Hao, Y., Fang, M., Xu, C., Ying, Z., Wang, H., Zhang, R., et al. (2021) A Graphene-Laminated Electrode with High Glucose Oxidase Loading for Highly-Sensitive Glucose Detection. Journal of Materials Science & Technology, 66, 57-63. [Google Scholar] [CrossRef] 
[3] Madden, J., Barrett, C., Laffir, F.R., Thompson, M., Galvin, P. and O’Riordan, A. (2021) On-Chip Glucose Detection Based on Glucose Oxidase Immobilized on a Platinum-Modified, Gold Microband Electrode. Biosensors, 11, Article 249. [Google Scholar] [CrossRef] [PubMed]
[4] Zha, S., Li, H., Law, G., Wong, K. and All, A.H. (2023) Sensitive and Responsive Upconversion Nanoprobes for Fluorescence Turn-On Detection of Glucose Concentration. Materials & Design, 227, Article ID: 111800. [Google Scholar] [CrossRef] 
[5] Jin, H., Zeng, W., Qian, W., Li, L., Ji, P., Li, Z., et al. (2024) Accelerated Reconstruction of ZIF-67 with Significantly Enhanced Glucose Detection Sensitivity. Nano Research, 17, 4737-4743. [Google Scholar] [CrossRef] 
[6] Chen, X., Dou, X., Qiu, W., Hong, Y. and Chen, Y. (2023) A Glucose-Sensitive Microgel Operating at Physiological Conditions for Glucose Detecting and Insulin Delivery. European Polymer Journal, 195, Article ID: 112236. [Google Scholar] [CrossRef] 
[7] Hou, Z., Gao, T., Liu, X., Guo, W., Bai, L., Wang, W., et al. (2023) Dual Detection of Human Motion and Glucose in Sweat with Polydopamine and Glucose Oxidase Doped Self-Healing Nanocomposite Hydrogels. International Journal of Biological Macromolecules, 252, Article ID: 126473. [Google Scholar] [CrossRef] [PubMed]
[8] Wu, M., Zhang, Y., Liu, Q., Huang, H., Wang, X., Shi, Z., et al. (2019) A Smart Hydrogel System for Visual Detection of Glucose. Biosensors and Bioelectronics, 142, Article ID: 111547. [Google Scholar] [CrossRef] [PubMed]
[9] Li, X., Lv, J., Zhao, J., Ling, G. and Zhang, P. (2024) Swellable Colorimetric Microneedles for Glucose Detection Based on Glucose Oxidase-Like Gold Nanoparticles. Analytica Chimica Acta, 1288, Article ID: 342152. [Google Scholar] [CrossRef] [PubMed]
[10] Rernglit, W., Teanphonkrang, S., Suginta, W. and Schulte, A. (2019) Amperometric Enzymatic Sensing of Glucose Using Porous Carbon Nanotube Films Soaked with Glucose Oxidase. Microchimica Acta, 186, Article No. 616. [Google Scholar] [CrossRef] [PubMed]
[11] Jarnda, K.V., Wang, D., Qurrat-Ul-Ain, Anaman, R., Johnson, V.E., Roberts, G.P., et al. (2023) Recent Advances in Electrochemical Non-Enzymatic Glucose Sensor for the Detection of Glucose in Tears and Saliva: A Review. Sensors and Actuators A: Physical, 363, Article ID: 114778. [Google Scholar] [CrossRef] 
[12] Ma, R., Wang, Y., Sha, Z., et al. (2024) Te-Au Nanowires with Multiple Enzyme-Like Activities for Glucose Detection. Journal of Materials Science, 59, 1-17.
[13] Han, Z., Zhang, X., Yuan, H., Li, Z., Li, G., Zhang, H., et al. (2022) Graphene Oxide/Gold Nanoparticle/Graphite Fiber Microelectrodes for Directing Electron Transfer of Glucose Oxidase and Glucose Detection. Journal of Power Sources, 521, Article ID: 230956. [Google Scholar] [CrossRef] 
[14] Chen, C., Fu, J., Chang, J., Huang, S., Yeh, T., Hung, J., et al. (2018) Bismuth Oxyfluoride/Bismuth Oxyiodide Nanocomposites Enhance Visible-Light-Driven Photocatalytic Activity. Journal of Colloid and Interface Science, 532, 375-386. [Google Scholar] [CrossRef] [PubMed]
[15] Siao, C., Chen, H., Chen, L., Chang, J., Yeh, T. and Chen, C. (2018) Controlled Hydrothermal Synthesis of Bismuth Oxychloride/Bismuth Oxybromide/Bismuth Oxyiodide Composites Exhibiting Visible-Light Photocatalytic Degradation of 2-Hydroxybenzoic Acid and Crystal Violet. Journal of Colloid and Interface Science, 526, 322-336. [Google Scholar] [CrossRef] [PubMed]
[16] Zhang, T., Yue, X., Gao, L., Qiu, F., Xu, J., Rong, J., et al. (2017) Hierarchically Porous Bismuth Oxide/Layered Double Hydroxide Composites: Preparation, Characterization and Iodine Adsorption. Journal of Cleaner Production, 144, 220-227. [Google Scholar] [CrossRef] 
[17] Lee, Y., Dai, Y., Fu, J. and Chen, C. (2017) A Series of Bismuth-Oxychloride/Bismuth-Oxyiodide/Graphene-Oxide Nanocomposites: Synthesis, Characterization, and Photcatalytic Activity and Mechanism. Molecular Catalysis, 432, 196-209. [Google Scholar] [CrossRef] 
[18] Cai, J., Zhang, Y., Qian, T., Li, X., Chen, Z. and Zhang, L. (2022) Bismuth Oxybromide/Bismuth Oxyiodide Nanojunctions Decorated on Flexible Carbon Fiber Cloth as Easily Recyclable Photocatalyst for Removing Various Pollutants from Wastewater. Journal of Colloid and Interface Science, 608, 2660-2671. [Google Scholar] [CrossRef] [PubMed]
[19] Luo, Y., Zhang, M., Yin, H., Yao, J., Chen, S. and Liu, X. (2019) One Pot Controllable Synthesis of Palygorskite/Bismuth Oxyiodide Hierarchical Microspheres for Improved Visible-Light Photocatalytic Performance. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 578, Article ID: 123573. [Google Scholar] [CrossRef] 
[20] Pei, Z. and Guo, H. (2023) Synthesis of Sio2-Doped Biox (X=Cl, Br) II-Type Heterojunctions and 2H-MoS2-Doped SiO2@Biox Z-Scheme Heterojunctions: A Comparative Study. Journal of Physics and Chemistry of Solids, 176, Article ID: 111236. [Google Scholar] [CrossRef] 
[21] Lv, J., Hu, Q., Cao, C. and Zhao, Y. (2018) Modulation of Valence Band Maximum Edge and Photocatalytic Activity of Biox by Incorporation of Halides. Chemosphere, 191, 427-437. [Google Scholar] [CrossRef] [PubMed]
[22] Wang, J., Bei, J., Guo, X., Ding, Y., Chen, T., Lu, B., et al. (2022) Ultrasensitive Photoelectrochemical Immunosensor for Carcinoembryonic Antigen Detection Based on Pillar[5]arene-Functionalized Au Nanoparticles and Hollow PANI Hybrid BiOBr Heterojunction. Biosensors and Bioelectronics, 208, Article ID: 114220. [Google Scholar] [CrossRef] [PubMed]
[23] Wang, J., Zhou, Q., Fan, C., Guo, X., Bei, J., Chen, T., et al. (2024) Ultrasensitive and Specific Photoelectrochemical Sensor for Hydrogen Peroxide Detection Based on Pillar[5]arene-Functionalized Au Nanoparticles and MWNTs Hybrid Biobr Heterojunction. Microchimica Acta, 191, Article No. 266. [Google Scholar] [CrossRef] [PubMed]
[24] Chen, J., Li, H., Zhou, X., Li, E., Wang, Y., Guo, Y., et al. (2017) Efficient Synthesis of Hollow Silica Microspheres Useful for Porous Silica Ceramics. Ceramics International, 43, 13907-13912. [Google Scholar] [CrossRef] 
[25] Wang, J., Guo, X., Zhou, Q., Cai, Y., Lu, B., Wang, Y., et al. (2024) Pillar[5]arene Functionalized Au NPs and BIOX (Cl/Br/I) Heterojunction Constructed the Enhanced Photo-Electrochemical Sensor for Ultrasensitive Detection of Serotonin. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 688, Article ID: 133511. [Google Scholar] [CrossRef] 
[26] Wang, J., Zhou, L., Bei, J., Zhao, Q., Li, X., He, J., et al. (2022) An Enhanced Photo-Electrochemical Sensor Constructed from Pillar[5]arene Functionalized Au NPs for Ultrasensitive Detection of Caffeic Acid. Talanta, 243, Article ID: 123322. [Google Scholar] [CrossRef] [PubMed]
[27] Xing, R., Yang, H., Li, S., Yang, J., Zhao, X., Wang, Q., et al. (2016) A Sensitive and Reliable Rutin Electrochemical Sensor Based on Palladium Phthalocyanine-MWCNTs-Nafion Nanocomposite. Journal of Solid State Electrochemistry, 21, 1219-1228. [Google Scholar] [CrossRef] 
[28] Wang, J., Lu, C., Chen, T., Hu, L., Du, Y., Yao, Y., et al. (2019) Simply Synthesized Nitrogen-Doped Graphene Quantum Dot (NGQD)-Modified Electrode for the Ultrasensitive Photoelectrochemical Detection of Dopamine. Nanophotonics, 9, 3831-3839. [Google Scholar] [CrossRef] 
[29] Wang, J., Zhou, L., Bei, J., Xie, M., Zhu, X., Chen, T., et al. (2022) An Specific Photoelectrochemical Sensor Based on Pillar[5]arenes Functionalized Gold Nanoparticles and Bismuth Oxybromide Nanoflowers for Bovine Hemoglobin Recognition. Journal of Colloid and Interface Science, 620, 187-198. [Google Scholar] [CrossRef] [PubMed]

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