极重型新生儿高胆红素血症治疗1例

Treatment of a Case of Severe Neonatal Hyperbilirubinemia

摘要: 随着人们对新生儿黄疸认识的深入及医疗机构对新生儿高胆红素血症的规范管理，极重型新生儿高胆红素血症目前在临床并不常见，该病在诊断上并不困难，但发现时已是极重型高胆红素血症，易发展为胆红素脑病，造成神经系统损伤，严重影响新生儿今后生长发育及健康，因此治疗上需光疗联合其他多种治疗措施，尽快将胆红素降低至安全阈值以下，减少胆红素脑病的发生。本病例患儿胆红素水平达到极重型，经过光疗，静脉输注白蛋白、免疫球蛋白、补液等治疗措施，早期积极干预，迅速降低了患儿胆红素水平，避免了胆红素脑病的发生，预后良好。

Abstract: With the deepening of people’s understanding of neonatal jaundice and the standardized management of neonatal hyperbilirubinemia by medical institutions, extremely severe neonatal hyperbilirubinemia is not common in clinical practice. The disease is not difficult to diagnose, but when it is discovered, it is already extremely severe hyperbilirubinemia, which is prone to develop into bilirubin encephalopathy and cause nervous system damage. Therefore, phototherapy combined with other multiple treatment measures is required for treatment to reduce bilirubin to below the safe threshold as soon as possible and reduce the occurrence of bilirubin encephalopathy. The bilirubin level of the child in this case reached an extremely severe level. After phototherapy, intravenous infusion of albumin, immunoglobulin, fluid infusion and other treatment measures, early active intervention quickly reduced the bilirubin level of the child, avoided the occurrence of bilirubin encephalopathy, and had a good prognosis.