中医体质与颈椎病相关性研究系统评价和Meta分析

Systematic Evaluation and Meta-Analysis of the Correlation between Traditional Chinese Medicine Constitution and Cervical Spondylosis

摘要: 目的：归纳颈椎病中医体质分布规律，对颈椎病中医体质分布类型进行研究，为中医药在预防和治疗颈椎病上提供更有利的循证医学证据。方法：检索CNKI、Wanfang、VIP数据库，纳入所有颈椎病中医体质的相关文献，采用Stata15.0软件进行单组率的Meta分析。结果：共纳入9项横断面研究，平和质、阳虚质、痰湿质分别占比为23% (11%, 35%)、18% (11%, 25%)、12% (11%, 14%)。平和质、阳虚质、痰湿质、血瘀质人群颈椎病患病风险的OR值分别为0.37 (0.27~0.49)、2.34 (1.70~3.21)、1.68 (1.39~2.04)、1.92 (1.40~2.64)。结论：颈椎病患者中平和质、阳虚质、痰湿质占比最多，并且阳虚质、痰湿质、血瘀质为颈椎病发生的危险因素，平和质为保护因素。期望有更高质量、大样本的队列研究，为未来防治颈椎病提供高效的参考依据。

Abstract: Objective: To summarize the distribution of TCM constitution of cervical spondylosis, explore the distribution law of TCM constitution of cervical spondylosis, and provide more favorable evidence-based medical evidence for TCM prevention and treatment of cervical spondylosis. Methods: We searched CNKI, Wanfang, and VIP database, and included all the relevant literature on TCM constitution of cervical spondylosis. We used Stata15.0 software to conduct a meta-analysis of single-group rate. Results: A total of 9 cross-sectional studies were included, and the proportions of peaceful quality, yang deficiency quality and phlegm-dampness quality were 23% (11%, 35%), 18% (11%, 25%) and 12% (11%, 14%), respectively. The OR values of the prevalence risk of cervical spondylosis in the population with mild, yang deficiency, phlegm dampness and blood stasis were 0.37 (0.27~0.49), 2.34 (1.70~3.21), 1.68 (1.39~2.04) and 1.92 (1.40~2.64), respectively. Conclusion: This study provides a more favorable evidence-based clinical basis for the prevention of cervical spondylosis with traditional Chinese medicine. Yang deficiency, phlegm-dampness and blood stasis are the risk factors of cervical spondylosis, and peace is the protective factor. In view of the medium quality of the included literature, it is expected to have higher quality and large sample studies to reduce the occurrence of bias and provide efficient reference basis for the prevention and treatment of cervical spondylosis in the future.