围绝经期失眠伴焦虑抑郁的中西医治疗研究进展

Progress in the Treatment of Perimenopausal Insomnia with Anxiety and Depression

摘要: 失眠伴焦虑抑郁是女性围绝经期临床上一种常见的生理–心理疾病，中医学称之为郁证。严重者可给患者自身和家庭带来极负面的影响，对临床治疗也加剧挑战。且长期焦虑抑郁会导致失眠，长期失眠亦会导致焦虑抑郁，二者互为因果渐进加剧病情。围绝经期患者中约为68%会发生失眠伴焦虑抑郁状态，因此其治疗现状也逐渐受到国内外许多学者的广泛关注。现代医学在中医和西医在临床上有诸多治疗方法，中医药确实可提高围绝经期失眠伴焦虑抑郁的有效率，中西药结合亦存在较好的临床效果，但也缺乏确切的辩证分型、作用机制等相关疑问。

Abstract: Insomnia concurrently associated with anxiety and depression constitutes a prevailing physiological and psychological malady among females during perimenopause, which is denominated depressive syndrome in traditional Chinese medicine. Severe cases can exert an extremely adverse impact on patients and their families, and concurrently exacerbate the challenge of clinical therapeutics. Furthermore, protracted anxiety and depression will engender insomnia, while chronic insomnia will also incite anxiety and depression. The two mutually cause and effect, gradually deteriorating the condition. Approximately 68% of perimenopausal patients will undergo insomnia accompanied by anxiety and depression, thereby its treatment status has gradually garnered extensive attention from numerous scholars both domestically and internationally. Modern medicine encompasses diverse clinical treatment modalities in both traditional Chinese medicine and Western medicine. Traditional Chinese medicine can undoubtedly augment the efficacy of perimenopausal insomnia concurrently associated with anxiety and depression. The combination of traditional Chinese and Western medicine also yields auspicious clinical outcomes; however, it still lacks precise dialectical classification, mechanism of action, and other related matters.