环状RNA在炎症性疾病中的研究进展
Advances in Research on Circular RNA in Inflammatory Diseases
DOI: 10.12677/md.2024.143049, PDF,   
作者: 曹 晶*, 李 勇, 陈 斌, 喻廷凤, 何正兵：益阳市中心医院呼吸内科，湖南 益阳
关键词: 环状RNA；炎症；炎症性疾病；Circular RNA； Inflammatory； Inflammatory Diseases
摘要: 炎症性疾病(inflammation disease, ID)是泛指一类伴有炎症反应的一系列疾病，其发病机制复杂。环状RNA (circular RNA, circRNA)是一类经过反向剪接形成的具有闭合环状结构的、大量存在于真核转录组中的非编码RNA，是目前生命科学和医学领域研究的热点分子，其在不同疾病中呈差异性表达，参与机体各类生理和病理过程。本文将对环状RNA在肿瘤、心血管疾病、神经系统疾病、糖尿病、自身免疫性疾病及感染性疾病等ID中的最新研究进展进行综述，以期为环状RNA在基础和临床的研究提供参考。
Abstract: Inflammatory Disease refers to a series of diseases accompanied by inflammatory reactions, and its pathogenesis is complex. Circle RNA is a kind of non-coding RNA with closed ring structure formed by reverse splicing, which exists in a large number of eukaryotic transcriptome. It is a hot molecule in the field of life science and medicine. Studies have found that it is differentially expressed in different diseases and participates in various physiological and pathological processes. In this review, we will review the recent research progress of circRNAs in inflammatory diseases of cancer, cardiovascular disease, neurological disease, diabetes, autoimmune diseases and infectious diseases. In order to provide theoretical basis for circrnas in clinical and basic research.
文章引用：曹晶, 李勇, 陈斌, 喻廷凤, 何正兵. 环状RNA在炎症性疾病中的研究进展[J]. 医学诊断, 2024, 14(3): 344-351. https://doi.org/10.12677/md.2024.143049

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