唾液酸转移酶综述
A Review of Sialyltransferase
DOI: 10.12677/amb.2024.133025, PDF,   
作者: 李 昊, 甄庚尧, 徐艳秋, 朱德强, 刘新利：齐鲁工业大学(山东省科学院)，生物工程学部，山东 济南；李 宁, 周焕霞, 曹建帮, 高学秀：山东星光首创生物科技有限公司，山东 乐陵
关键词: 唾液酸转移酶；Cazy家族分类；酶学性质；构效关系；Sialyltransferase； Classification of the Cazy Family； Enzymatic Properties； Structure-Activity Relationship
摘要: 唾液酸在人的细胞识别、分化、迁移和信号识别等重要生理活动中具有重要的作用。在其生理功能的发挥过程中，唾液酸转移酶是不可或缺的重要参与者，其将唾液酸转移到单糖或寡糖的末端，因而唾液酸转移酶被越来越多的研究者所关注。本论文梳理了前期文献研究的主要成果，将从其来源、分类、结构、酶学性质以及催化机理等方面进行综述，以供研究者参考。
Abstract: Sialyltransferase plays an important role in important physiological activities, such as cell recognition, differentiation, migration, and signal recognition in humans. In the process of its physiological function, sialyltransferase is an indispensable and important participant. It transfers sialic acid to the end of monosaccharides or oligosaccharides, so sialyltransferase is receiving increasing attention from researchers. This paper reviews the main achievements of previous literature research, including their sources, classifications, structures, enzymatic properties, and catalytic mechanisms, for reference by researchers.
文章引用：李昊, 甄庚尧, 李宁, 周焕霞, 曹建帮, 高学秀, 徐艳秋, 朱德强, 刘新利. 唾液酸转移酶综述[J]. 微生物前沿, 2024, 13(3): 236-246. https://doi.org/10.12677/amb.2024.133025

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