强脉冲光治疗睑板腺功能障碍性干眼症的临床研究

Clinical Study on the Treatment of Meibomian Gland Functional Dry Eye Syndrome with Strong Pulsed Light

摘要: 目的：探究强脉冲光(IPL)治疗睑板腺功能障碍性干眼症的临床疗效。方法：选取我院2022年10月至2023年12月确诊为睑板腺功能障碍性干眼症患者62例，随机分为对照组(31例)和观察组(31例)。对照组及观察组均采取传统基础治疗，观察组在对照组基础上予以IPL治疗，比较两组治疗前后效果。结果：两组经治疗2月后，眼表疾病指数评分，睑板腺功能评分均比治疗前降低，且观察组低于对照组(P < 0.05)；两组泪膜破裂时间(TBUT)、泪液分泌试验(SIT)和角膜荧光素钠染色(CFS)方面均比治疗前改善，且观察组TBUT、SIT显著长于对照组，CFS小于对照组(P < 0.05)。结论：强脉冲光治疗睑板腺功能障碍性干眼症的效果明显。

Abstract: Objective: To investigate the clinical effect of intense pulsed light (IPL) on meibomian gland dysfunction related dry eye. Methods: 62 patients diagnosed with meibomian gland dysfunction dry eye syndrome in our hospital from October 2022 to December 2023 were randomly divided into a control group (31 cases) and an observation group (31 cases). Both the control group and the observation group received traditional basic treatment, while the observation group received IPL treatment on top of the control group. The effects of the two groups before and after treatment were compared. Results: After 2 months of treatment, the eye surface disease index score and meibomian gland function scores of both groups decreased compared to before treatment, and the observation group was lower than the control group (P < 0.05). Both groups showed improvement in tear film breakup time (TBUT), tear secretion test (SIT), and corneal fluorescein sodium staining (CFS) compared to before treatment, and the observation group had significantly longer TBUT and SIT than the control group, while CFS was lower than the control group (P < 0.05). Conclusion: The treatment of meibomian gland functional dry eye with strong pulsed light has a significant effect.