氧化应激与腹膜透析患者动脉粥样硬化研究进展
Research Progress of Oxidative Stress and Atherosclerosis in Patients Undergoing Peritoneal Dialysis
DOI: 10.12677/acm.2024.14112897, PDF,    科研立项经费支持
作者: 张瑜媛, 马春慧：右江民族医学院研究生学院，广西 百色；黄 鹏*：右江民族医学院附属医院肾内科，广西 百色
关键词: 腹膜透析；氧化应激；动脉粥样硬化；Peritoneal Dialysis； Oxidative Stress； Atherosclerosis
摘要: 腹膜透析(peritoneal dialysis, PD)作为慢性肾脏病(chronic kidney disease, CKD)患者的重要治疗方式，为其生存质量的改善带来了积极影响。然而，PD患者动脉粥样硬化(atherosclerosis, AS)的发生率明显高于普通人群，且具有较高的致残、致死率。越来越多的研究表明，氧化应激(oxidative stress, OS)在PD患者AS的形成和演进中扮演着举足轻重的角色，故本文旨在综合阐述氧化应激与腹膜透析患者动脉粥样硬化之间的关系及相关研究的最新进展，为临床治疗和预防提供有价值的参考。
Abstract: As an important treatment for patients with chronic kidney disease (CKD), peritoneal dialysis (PD) has a positive impact on the improvement of their quality of life. However, the incidence of atherosclerosis (AS) in patients with PD is significantly higher than that in the general population, and has a higher rate of disability and mortality. More and more studies have shown that oxidative stress (OS) plays an important role in the formation and evolution of AS in patients with PD. Therefore, this paper aims to comprehensively explain the relationship between oxidative stress and atherosclerosis in peritoneal dialysis patients and the latest progress of related research, so as to provide valuable reference for clinical treatment and prevention.
文章引用：张瑜媛, 马春慧, 黄鹏. 氧化应激与腹膜透析患者动脉粥样硬化研究进展[J]. 临床医学进展, 2024, 14(11): 433-439. https://doi.org/10.12677/acm.2024.14112897

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