自组装工艺在药食同源功能食品中的应用
Applications of Self-Assembly Processing in Functional Foods Based on Food-Medicine Dual Purpose
DOI: 10.12677/hjfns.2025.146086, PDF,   
作者: 尹小明*：大闽食品(漳州)有限公司，福建 漳州；上海交通大学药学院，上海；上海吉罗恩生物科技有限公司，上海；高艺航, 阮文浩, 张 玺, 徐义明：大闽食品(漳州)有限公司，福建 漳州；上海吉罗恩生物科技有限公司，上海；福建省饮料用植物提取技术企业重点实验室，福建 漳州
关键词: 功能食品；生物利用度；药食同源；自组装；Functional Foods； Bioavailability； Food-Medicine Dual Purpose； Self-Assembly
摘要: 随着人们对健康养生和药食同源功能食品的关注持续升温，传统中药复方中的“自组装”理念为现代食品加工提供了新的思路。中药复方由多种活性成分组成，这些小分子可通过氢键、π-π堆积、静电等非共价相互作用自发形成纳米结构，从而提高难溶性成分的溶解度和生物利用度。同时，许多药食同源植物既可药用又可作为食材，它们富含多酚、黄酮和多糖等功能物质，可通过自组装载体实现安全高效的递送。本文在阐述中药复方自组装的常见类型的基础上，进一步阐述自组装工艺在药食同源功能食品加工中的应用，介绍典型研究案例及其对活性成分溶解度、稳定性和生物利用度的提升等关键问题。
Abstract: As public interest in health maintenance and dual-use functional foods continues to grow, the concept of “self-assembly” embedded in traditional Chinese multi-herb formulae offers fresh perspectives for modern food processing. Composed of numerous active constituents, these formulae can spontaneously form nanostructures via noncovalent interactions—such as hydrogen bonding, π-π stacking, and electrostatic forces—thereby enhancing the solubility and bioavailability of poorly soluble compounds. Meanwhile, many botanicals designated as food and medicine dual purpose serve both medicinal and culinary roles and are rich in polyphenols, flavonoids, and polysaccharides; these bioactives can be delivered safely and efficiently through self-assembled carriers. Building on an overview of common self-assembly types observed in traditional Chinese medicine (TCM) formulae, this review focuses on applications of self-assembly processes in the manufacturing of functional foods derived from food and medicine dual purpose materials, highlighting representative case studies and discussing key issues, including improvements in the solubility, stability, and bioavailability of active ingredients.
文章引用：尹小明, 高艺航, 阮文浩, 张玺, 徐义明. 自组装工艺在药食同源功能食品中的应用[J]. 食品与营养科学, 2025, 14(6): 782-791. https://doi.org/10.12677/hjfns.2025.146086

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